How to Make a Neuron and How Pioneer Factors May Find Their Targets
10/7/2019; 58 minutes
Marius Wernig, MD, PhD, discusses how his lab has worked to convert non-neuronal cell types (lymphocytes, pluripotent stem cells, fibroblasts, hepatocytes, lymphocytes) to neurons. The lab is now working on identifying the molecular mechanisms underlying induced lineage fate changes, the phenotypic consequences of disease-causing mutations in human neurons and other neural lineages. (#35063)
Links & Resources
Explore more in this series: Sanford Stem Cell Institute Seminar Series
