Nature has been running chemistry experiments for over 4 billion years—yet today, much of modern organic chemistry still depends on wasteful, resource-heavy methods that rely on oil-based solvents. These solvents aren't recycled, and when burned, they release CO2, adding to climate change. But what if chemistry could be done differently? Bruce Lipshutz, Distinguished Professor of Chemistry at UC Santa Barbara, shows how it's possible to carry out organic reactions in water—nature's own solvent. His research demonstrates that chemistry in water isn't just more sustainable, it can also be faster, cheaper, and more effective than traditional approaches. (#41029)