UC San Diego's Last Gift study aims to identify where HIV hides in the body of individuals who are terminally ill from a disease other than HIV, like cancer, ALS, or heart disease. Karine Dubé, DrPH, MPhil, Sarah Gianella Weibel, MD, Andy Kaytes, and Susanna Concha-Garcia discuss the ethical implications of the study, the experiences of the participants, the study components, and what can be learned. (#37319)