Researchers at the UC San Diego Stem Cell Program have used a rare disorder, Aicardi Goutieres (AGS), to explore fundamental brain mechanisms. By utilizing cortical organoids, or brains in a dish, they have tracked neurodevelopment while discovering new information about the relationship between retrotransposons and neuroinflammation. (Spanish Translation) (#32917)

related programs

Genetics

1. 

   Getting to the Heart of Cell Fate Control
2. 

   Engineering ‘Selfish’ Genes in Mice: Benefits and Risks - Exploring Ethics
3. 

   Genetically Engineered Plants and Climate Change - Exploring Ethics

Inflammation and Disease

1. 

   Reconstruindo o cérebro em uma placa de Petri: ocorrência de neuroinflamação causada por retrotransposons- Reconstructing the Brain in a Dish: Emergence of Neuroinflammation from Retrotransposons (Portuguese Translation)
2. 

   The Appeal of Osteopathic Medicine with Hollis King, DO; Michael Kurisu, DO; and Paul J. Mills — UC Wellbeing Channel
3. 

   The Intersection of Behavior and Mental Health Through the Lens of Inflammation, HIV, Alzheimer's Disease and More with Igor Grant - On Our Mind

Neurology

1. 

   What Role Do Genetics Play in Alzheimer’s? - On Our Mind
2. 

   Studying the Progression of Alzheimer's Disease with Bradley Hyman MD PhD - Shiley Endowed Lecture
3. 

   Progenitor Cell-Based Modeling and Treatment of Glial Disease

Neuroscience

1. 

   Studying the Progression of Alzheimer's Disease with Bradley Hyman MD PhD - Shiley Endowed Lecture
2. 

   TBR1 and AUTS2: Sequential Regulators of Gene Expression in Cortical Development with Overlapping Neurodevelopmental Syndromes
3. 

   CARTA: Imagination and Human Origins: Adrie & Alfons Kennis - Using Imagination to Create Reconstructions of Ancient Hominins

Pediatrics / Family Medicine / Child Development

1. 

   Cranial Remolding Helmets
2. 

   Cerebral Palsy: A View From Both Sides
3. 

   A Team Approach to Care for Children with Cerebral Palsy

Regenerative Science

1. 

   Getting to the Heart of Cell Fate Control
2. 

   TBR1 and AUTS2: Sequential Regulators of Gene Expression in Cortical Development with Overlapping Neurodevelopmental Syndromes
3. 

   CARTA: Imagination and Human Origins: Alysson Muotri - Reconstructing the Neanderthal Mind in a Dish

Stem Cell Research

1. 

   Getting to the Heart of Cell Fate Control
2. 

   TBR1 and AUTS2: Sequential Regulators of Gene Expression in Cortical Development with Overlapping Neurodevelopmental Syndromes
3. 

   Progenitor Cell-Based Modeling and Treatment of Glial Disease