Health and Medicine

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A look at PrEP, a prevention strategy for people at high risk for contracting HIV. Researchers at the University of California explain how pre-exposure prophylaxis (PrEP) works as they describe a four-year, multi-pronged study of men who have sex with men in Los Angeles and San Diego. Participants agree to take a Truvada pill daily to reduce their risk of getting infected by up to 99%. But will they follow through? Methods to increase adherence among the participants are also being tested, including daily reminders via text messages and tracking usage of the medication with special "Mems caps" for the pill bottles.

There is strong evidence to suggest that where you live determines your life expectancy as well as your overall health. Anthony B. Iton, MD, JD, MPH is Senior Vice President at The California Endowment, discusses the root causes of health inequity, mostly living conditions as a result of poverty and economic opportunity, and how interventions at multiple points can change health outcomes.

Early detection of Alzheimer's disease - before symptoms are visible - may be a key to stopping the disease's progression. What warning signs are researchers looking for and what tools can they use? Paul Aisen, MD joins William Mobley, MD, PhD to discuss optimal assessments for diagnosing the disease, novel tools making earlier diagnosis possible, and the road map to developing drugs to slow, halt, and prevent Alzheimer's. Recorded on 7/29/2014.

Studies measuring behavior and those examining brain size and function have helped to reveal a great deal about how cognition and emotions change with age. Increasingly, however, there is a recognition that additional insight about cognitive and emotional aging can come from investigating the role of blood-based biological factors, including telomere length, gene expression, and levels of circulating compounds related to immunity, stress-responsiveness, and cardiovascular health. This talk will review recent work in this area, with an emphasis on how such factors might be used in the future to help develop individualized interventions to maintain mental wellness into old age.

Can cancer cells be killed without harming the healthy cells around them? A new clinical trial is testing that hypothesis using a virus-based treatment. Learn how vaccinia, once used to eradicate smallpox, may be the key to more effective cancer fighting tools. Dr. Loren Mell joins Dr. David Granet to discuss current research and the importance of clinical trails for cancer patients.

What does the future hold for the treatment of Alzheimer's disease? Steven L. Wagner, PhD joins William Mobley, MD, PhD to discuss the development of new drugs to aid in the fight. Wagner describes amyloid plaques as "the cholesterol of the brain" and is working to find a way to suppress its adverse effects.

In his talk, George Liu, MD, discusses community-associated MRSA infections (CA-MRSA) and the impact on public health.

Leading researchers, government officials, and physicians share their insights into the growing public health crisis of Alzheimer's disease.

Anorexia is the 3rd most common chronic illness among adolescents. Research shows that early detection and prompt intervention may prevent as many as two-thirds of patients from developing a more serious eating disorder. Dr. Sara Buckelew discusses how to identify an eating disorder, early intervention and prevention. Recorded on 11/05/2014.

According to the Lancet Commission on Global Surgery, more than 2 billion people worldwide lack access even to basic surgical care. Lack of access to surgery can create permanent incapacities, with an estimated 11-15% of disability in the world due to surgically treatable conditions. Learn what is being done to make essential surgical services available to the world's poorest populations. Speakers include Gavin Yamey, Lead, Evidence to Policy Initiative, UCSF; Haile Debas, Director, UC Global Health Institute; and Paul Farmer, Kolokotrones University Professor of Global Health and Social Medicine, Harvard University. Recorded on 10/02/2014.

For many years, neglected tropical diseases have been just that: neglected. However a wave of new funding combined with novel tools are generating significant progress against conditions that afflict the most vulnerable populations. Learn about major breakthroughs on the horizon for these tragic diseases. Speakers include Mary Wilson, Visiting Professor, UCSF; Eva Harris, Professor and Director, Center for Global Public Health, UC Berkeley; Peter Hotez, Founding Dean, National School of Tropical Medicine, Baylor College of Medicine; Mark Rosenberg, President and CEO, The Task Force for Global Health and Roberto Tapia Conyer, Director General, Carlos Slim Foundation. Recorded on 10/02/2014.

No country in human history has reduced mortality rates as quickly as Rwanda in the last 15 years. But are the circumstances that have allowed Rwanda to make this progress unique? Ambassador Eric Goosby moderates a discussion with Paulin Basinga of the Bill & Melinda Gates Foundation and Paul Farmer of Partners in Health about what is replicable from Rwanda and what other countries might learn from its experience. Recorded on 10/02/2014.

Lincoln Chen, President, China Medical Board and Jaime Sepulveda, Executive Director, Global Health Sciences, UCSF conclude the 2014 Conference on the Science of Global Health: What's Next? Recorded on 10/02/2014.
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